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The dysregulation of anti-inflammatory cytokines, such as interleukin-13 [50] and transforming growth factor-beta1 [51], compromises the critical balance with pro-inflammatory signals, thereby preventing the resolution of inflammation and leading to its chronic persistence

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Adopting an established protocol 74 , we derived microglia from a CRISPRi hiPSC cell line that allows rapid generation of microglia through inducible expression of transcription factors and allows knockdown of endogenous genes

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1995;90:21342139 Khoo TK, Vege SS, Abu-Lebdeh HS, Ryu E, Nadeem S, Wermers RA

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[10] Actinic cheilitis [edit] Also termed "solar cheilosis", actinic cheilitis is the result of chronic over-exposure to ultraviolet radiation in sunlight

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