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Pre-existing mitochondrial dysfunction due to aging, diabetes, or ischemia creates a permissive environment for cuproptosis by depleting GSH and reducing SOD2 activity, thereby compromising the organelle's ability to chelate copper and neutralize mtROS [145, 146]

The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

Historically, it has been used in spycraft and wartime for sensitive communications, but the more familiar applications today center on online data

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This means it offers no protection against microbial growth once opened or after the peptide has been added