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Anti-tumor activity of the type I PRMT inhibitor, GSK3368715, synergizes with PRMT5 inhibition through MTAP loss

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Morris J.G

however, their direct application in clinical practice remains limited at this time

However, few reports support the elevation of antioxidant proteins such as HO-1 and catalase following clinical treatment with NAC, denoting that there may be a direct or even indirect oxidant-scavenging action of NAC [36,55]

A positive association between aconitase activity and GSH/GSSG was found in both cerebellum ( P =0.01) and BA22 ( P =0.03) in our combined case and control cohort (correlation coefficients=0.46 and 0.45, respectively)