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pylori secreted GGT decreased the expression of glutamine and -KG in gastric epithelial cells, increased the expression of histones H3K9me3 and H3K27me3, and activated the Wnt signaling pathway through RPL15 expression, ultimately changing the biological characteristics of the gastric epithelium and promoting the occurrence of gastric cancer

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There were minimal microbiome differences between lean and obese controls, suggesting that diet composition and adiposity had limited effects