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recently showed that intracellular Cu induces a novel form of regulated cell death characterized by the aggregation of lipoylated mitochondrial enzymes and a loss of FeS proteins

In: Natural Small Molecule Drugs from Plants

Open Biol

48 When intracellular irons are deficient, IRP1 binds to the IRE of TfR1 and ferritin, thus increasing the iron uptake and reducing iron storage
