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When both are active simultaneously, UV exposure triggers melanin synthesis (the intended effect) while also producing localized oxidative stress (the photosensitizer's effect)

Excessive amounts of n-3 and n-6 PUFAs triggered ferroptosis under acidosis, which mimics tumor microenvironment conditions 122

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Due to the conjugation of a double bond in the, , -position to the aldehydic functionality of CA, it is capable of undergoing Michael-type addition in form of an electrophilic reaction pathway, which morphs reductive GSH into oxidative GSSG