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Through the metabolic control molecular network, immune cells can switch between pro-inflammatory and anti-inflammatory states, and their abnormal regulation is closely related to IBD, rheumatoid arthritis, and tumor immune imbalance (19, 20)

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The dietary supplement must not be used as a substitute for a varied diet

However, whether these factors are causally related to CAD has been questioned in MR studies [45, 46], and we found no difference by sex in the risk factors