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In rodents, inhibiting the glutamate-cysteine ligase enzyme depleted the brain GSH, inducing cognitive symptoms like that observed in schizophrenia (Gysin et al

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Estrogen dominance is the condition of increased estrogen levels relative to progesterone levels in the body

Psychiatric conditions, especially mood disorders, frequently coexist with nociplastic pain, suggesting a bidirectional relationship due to shared risk factors like trauma and common disease mechanisms involving neurotransmitters
