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3.6 Inflammation Inflammation is a key driver in OSF pathogenesis, both as a cause and consequence of fibrotic change

[DOI] [PMC free article] [PubMed] [Google Scholar] 216.Wallach J., Kang H., Colestock T., Morris H., Bortolotto Z.A., Collingridge G.L., Lodge D., Halberstadt A.L., Brandt S.D., Adejare A

It works specifically within the gut to reduce immune overactivation and calm inflammatory cytokine activity particularly relevant for patients with IBD, Crohns, colitis, or persistent mucosal inflammation

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We also detected a loss of the neuronal cell marker NeuN and an activation of cleaved caspase-3 (Fig
