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Why have antioxidants failed in clinical trials

Cancer Research, 80 (2), 319333

A previous study demonstrated that HFD-fed, STZ-induced, insulin-resistant diabetic mice are good models for patients with T2DM that have risk factors for obesity and distinct metabolic characteristics (35)

Furthermore, none of these two subgroups showed significant differences (Table 3) in the mean changes (IV: SMD, 0.12

J Am Coll Cardiol 49: 22312237, 2007
