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( Clinical studies have confirmed elevated iron content specifically in coronary plaques from patients with acute coronary syndrome compared to stable coronary artery disease ( 5.3.2 Protection against ferroptosis in ischemic myocardium after coronary events Following coronary artery occlusion, the resulting myocardial ischemia-reperfusion injury involves extensive ferroptotic cardiomyocyte death

IGF1, Insulin-like growth factor 1
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miR-23a and miR-23b have also been shown to downregulate glutaminase (GLS), thereby disrupting glutamine metabolism

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