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10.1021/acs.jnatprod.1c00367 127 JiaoY.YaoB.ZhouQ.LuoX

both antibiotic use and germ-free conditions suppress the expression of CYP7A1 and CYP27A1, key enzymes involved in BA production based on animal mechanistic studies ( Clostridium and Bifidobacterium , as observed in human associative studies (Mulak, 2021)

doi: 10.1038/ki.1994.45

As a result, the binding ability of NF-B to DNA is reduced, leading to decreased expression of proinflammatory genes ( Table 2

A systematic review of Sec24 cargo interactome
