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Work in J.S.B.s laboratory is supported by the Intramural Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (ZIA HD001607)

Experimental Procedure Study design A randomized, double-blind, placebo-controlled trial in health human adults was conducted

Shortly afterwards the cause of the disease was identified as impaired cystathionine -synthase enzyme activity (30)