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Increased risk of blood clots: Smoking can make your blood more prone to clotting by affecting platelet function and promoting the formation of blood clots

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In UCSF's CANDIDE study, Leila Mohammadi, MD, PhD, lead clinical investigator, found that chronic cannabis smokers had similar vascular functional defects to those of chronic tobacco smokers, including poorly functioning arteries, and blood serum that inhibited important properties of cultured endothelial cells (the inner lining of blood vessels)

This study has certain limitations

Electronic cigarette use in the European Union: analysis of a representative sample of 27 460 Europeans from 28 countries