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Indeed, within the first 4 days of quitting, initial caffeine clearance decreased significantly by 36% ( CYP1A1, another enzyme influenced by smoking, is regulated by aryl hydrocarbons in cigarette smoke, like benzo [a]pyrene, benzo-fluorene, tetrachlorodibenzo-p-dioxin, and fluoranthene

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"Public health policies should not only be reassuring but also reflect the complete evidence

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