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Even with their significant potential benefits, however, GLP-1 RAs come with safety warnings for patients to speak with their doctor before starting treatment if they have a history of diabetic retinopathy

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Simonsen E., Lund L.C., Ernst M.T., et al

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While SUSTAIN-6 and REWIND trials examined GLP-1 RA in diabetics with different cardiovascular risk profile, The Harmony Outcomes study enrolled patients with T2D and established atherosclerotic cardiovascular disease (ASCVD)