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This dual crisis has catalyzed a pharmaceutical revolution, most notably in the development of highly effective GLP-1 receptor agonists

The search included terms such as small molecule GLP-1 receptor agonists, oral GLP-1 receptor agonists, Danuglipron, Orforglipron, and Aleniglipron. Additionally, information on ongoing clinical trials involving small molecule GLP-1 receptor agonists was retrieved from the ClinicalTrials.gov database using the same keywords

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Angela Fitch, cofounder and chief medical officer of knownwell, an obesity care and primary care provider

A key differential side effect for Retatrutide is a transient, dose-dependent increase in heart rate observed in the clinical trials, which necessitates careful cardiac screening and monitoring by a supervising physician