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Description
In individuals with obesity, the brain's reward centres may respond more intensely to food cues, whilst satiety signals may become blunted

How significant is this adverse signal

doi: 10.1097/HCO.0000000000000673 17 FerrarioCMStrawnWB

Further reading: Wegovy tablets vs orforglipron Neither option is automatically better for everyone

These changes emerge gradually over months and are often noticed by others before the individual themselves