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[DOI] [PubMed] [Google Scholar] 73.Vertongen P, et al
A systematic search of PubMed, Scopus, and Web of Science was conducted up to December 2024 according to PRISMA guidelines

Glucagon-like peptide 1 receptor activation: anti-inflammatory effects in the brain

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As a result, the half-life was extended to 1516 days (compared to the one-week duration of analogs like semaglutide or tirzepatide) while maintaining equivalent potency, opening the door for once-monthly instead of weekly administration