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Key milestones highlighted in this timeline: 1999 Orlistat (Xenical) The first long-term FDA-approved anti-obesity medication of the modern era
Studies are demonstrating a plethora of positive effects on cardiovascular health, renal disease and liver disease, which may be directly related to the mitigation of the diabetes or obesity-associated risks of these complications or possibly direct protective effects
these signals are hypothesis-generating and should not be interpreted as confirmed causal risks
