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doi: 10.1210/en.2002-220405 126 MaidaAHansotiaTLonguetCSeinoYDruckerDJ

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Tirzepatide is the active ingredient in Zepbound, a GLP-1 receptor agonist

As research has progressed, it has been revealed that vagal sensory neurons distributed in the intestinal and hepatic portal regions play a crucial role in sensing circulating GLP-1 and mediating its physiological actions

Drop back by at least one escalation step and work up again
