glp 1 mechanism of action weight loss Reduction with GLP-1 Agonists and Paths for Discontinuation While Maintaining Weight GLP-1 Receptor Agonists as Treatments

EMPA-KIDNEY Collaborative Group, Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, et al

Supplementary Table 3 indicates the meta-regressions

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All we're proposing to clinicians is Hey, think about the patients who are at risk and have a strategy to monitor and mitigate that risk." In a secondary analysis, the scientists found that weight loss alone did not explain the increased risk, suggesting other mechanisms of action may be at play