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At 104 weeks (2 years), patients in this subgroup reached 30.3% average weight loss confirming that retatrutide doesn't plateau at the primary endpoint and continues to improve with extended treatment
[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Janssen L.G.M., Nahon K.J., Brack K.F.M., van den Broek D., Smit R., Sardjoe Mishre A.S.D., Koorneef L.L., Martinez-Tellez B., Burakiewicz J., Kan H.E., et al

doi: 10.1172/jci.insight.170419

Patients who received 5-mg injections lost roughly 12 pounds over 40 weeks, while patients who received 15 mg lost about 23 pounds of body weight
