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These dual receptor pharmacology studies establish the molecular basis of incretin co-agonism and characterise the signalling architecture distinguishing Tirzepatide from selective GLP-1R monoagonists

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[DOI] [PMC free article] [PubMed] [Google Scholar] 144.Marcellin P., Gane E., Buti M., Afdhal N., Sievert W., Jacobson I.M., Washington M.K., Germanidis G., Flaherty J.F., Aguilar Schall R., et al