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Incretin-based therapies The year 2021 welcomed a game changer in the form of semaglutide for treatment of T2D in Singapore: Once-weekly subcutaneous (SC) semaglutide 1 mg (Ozempic®) and daily oral (PO) semaglutide (Rybelsus®)

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Furthermore, dual-action compounds engaging GLP-1 combined with glucose-dependent insulinotropic polypeptide (GIP) or glucagon pathways, alongside triple agonists incorporating all three receptors activation, have exhibited enhanced therapeutic potential