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It's important to note that high-quality evidence regarding non-diabetic retinopathy eye conditions is still evolving

HernandezAFGreenJBJanmohamedSD'Agostino RBSrGrangerCBJonesNPet alAlbiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (harmony outcomes): a double-blind, randomised placebo-controlled trial

This is particularly evident in specific cardiovascular conditions such as heart failure with preserved ejection fraction (HFpEF), for which effective treatments are scarce

Orforglipron is an oral GLP-1 agonist that could eliminate the need for injections entirely

If needle phobia is a particular issue, discussion of options that have the needle hidden and/or have a pre-attached needle, which require minimal handling by the patient, could be considered