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doi: 10.1016/j.eclinm.2025.103363
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For context on what people typically eat on each medication: Mounjaro (tirzepatide) Mounjaro typically reduces calorie intake by 30 to 40% in the first few months as the dose escalates

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Effect of DPP4 Inhibition on the Cardiovascular System In several in vitro and pre-clinical studies, DPP4 inhibitors have been shown to exert important protective effects on the cardiovascular system