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As Fig 3B reveals, I-M-150847 enhances GSIS in a dose-dependent manner, the increase is comparable to liraglutide at 100nM and 1M concentration at 30 minutes post-treatment with the agonists despite comparatively reduced cAMP accumulation upon I-M-150847 treatment

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doi:10.1016/S0196-9781(00)00287-4 47