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In addition, liraglutide-mediated suppression of glycogen synthase kinase 3- (GSK-3) and caspase-3 activation in murine hearts was not evident in GLP-1R knockout mice (Noyan-Ashraf et al., 2009), confirming that these effects are receptor-dependent

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Some may preferentially act on brain centres of appetite control, others more on pancreatic insulin secretion

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