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Description
The Gila monster (Heloderma suspectum), a unique lizard known for its binge-eating behavior, produces the hormone exenatide, the basis for diabetes medications such as Ozempic and Mounjaro
Recent Findings Retatrutide is the first triple agonist (acting on GLP-1/GIP/glucagon receptors) with published phase 2 data in people with obesity as well as in people with T2D
Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can reduce CV risk in patients with T2D, and both are recommended by the American Diabetes Association to reduce the risk of major cardiovascular events (MACE)
This is the unlikely journey from desert predator to medical marvel.
Background Since the SUSTAIN-6 trial, which noted early worsening of retinopathy with semaglutide (HR 1.76
