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Similar efficacy of DPP-4 inhibitors to either metformin or pioglitazone was also shown in formerly drug-nave patients who did not reach glycaemic goals with non-pharmacological interventions

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These sweeteners may come from plant sources, undergo less processing, or have a lower glycemic index (GI), making them more suitable for people with dietary restrictions, including diabetics, GLP-1 users, and those following ketogenic or paleo diets

Liraglutide-induced acute kidney injury