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doi: 10.1016/S2213-8587(21)00203-5

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However, when we start to treat massive numbers of people with less curated care, that is when we have to watch out for adverse effects. That means more studies

The reduction of cardiovascular events is not only related to anti-diabetic properties, but also to pleotropic effects leading to the reduction of the residual cardiovascular risk, that has been defined as the risk of progression of CV events (MACE or HF) that remains after the optimal glycaemic control in T2DM patients, and it seems to be related to meta-inflammation, defined as a low-grade chronic and sterile inflammatory status

After 6 months, those taking the semaglutide had average blood sugar reductions of 0.6% to 1.1%, with bodyweight reduction of around 5 pounds for the 14-mg dose