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Standard tirzepatide dosing starts at 2.5 mg weekly for the first four weeks, then increases to 5 mg

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Importantly, Zepbound carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)