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GLP-1s were associated with a significant reduction in body weight in 15 studies and improved glycemic control in eight studies enrolling people with mental illness

There are also concerns regarding potential drug-interactions and a reduction in long-term efficacy due to tachyphylaxis [73]

Retatrutide is now being studied as a triple-receptor medication that may shape the future of obesity medicine, but it remains investigational and should not be obtained from unverified online sellers

Diarrhea often occurs due to reduced nutrient absorption , particularly fats, which creates an osmotic effect that draws water into the intestines
Karagiannis T, Bekiari E, Tsapas A