jama glp-1 π Most viewed this week from JAMA: In patients with cardiometabolic #HFpEF, #semaglutide and #tirzepatide reduced the risk of hospitalization for heart failure or all-cause mortality vs sitagliptin, but tirzepatide offered no First Time: Orally Available GLP-1
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The authors explicitly suggest reframing switching as part of long-term optimization rather than discontinuation

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GLP-1 agonists may: Optimize high-risk patients before surgery Improve metabolic control Potentially reduce surgical risk But durable long-term outcomes in severe obesity still rely heavily on: Surgical intervention Lifelong follow-up Nutritional monitoring Multidisciplinary care The future may not be medicine vs surgery. It may be the intelligent integration of both

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If youre considering GLP-1 for weight loss, there are several key things to consider: GLP-1 side effects and your overall health, as well as your weight loss goals.