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Here is the framework experienced researchers use

Research from the STEP trials shows that gastrointestinal side effects peak during dose escalation periods and then gradually subside over 1 to 2 weeks at the new dose

"All of these things go together, and our goal is not only to make people smaller but also to make people healthier and stronger, which is so powerful." As more people explore the use of GLP-1 medicines -- KFF said about a third of adults had heard a lot about the drugs -- it will be integral for providers to practice holistic patient engagement and chronic disease management with their patients
