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Read the Full Regulatory and Clinical Disclosures Before Enrolling Comprehensive Telehealth Process: From Initial Assessment to Ongoing Compounded GLP-1 Care Step 1: Online Health Assessment Questionnaire (2-5 Minutes) The Join Josie intake process captures essential medical information required for healthcare provider evaluation including: Current weight, goal weight, weight history, and previous weight loss attempts Complete medication list including all prescription medications, over-the-counter drugs, vitamins, supplements, and herbal products Comprehensive allergy history and previous adverse medication reactions Medical conditions including cardiovascular disease, kidney disease, liver disease, thyroid disorders, pancreatitis history, gallbladder disease, gastrointestinal conditions, mental health diagnoses, eating disorders Reproductive and hormonal status (perimenopause, menopause, postmenopause, pregnancy potential, current pregnancy, breastfeeding, PCOS diagnosis) Previous GLP-1 medication exposure and response if applicable Family medical history particularly medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Government-issued photo identification upload for prescriber verification (federal legal requirement for prescription medication dispensing) Health Information Privacy Protection: All health information submitted through Join Josie platform is protected under HIPAA (Health Insurance Portability and Accountability Act) regulations governing protected health information (PHI)

52 These results, in part, supported the development of orforglipron as an orally delivered GLP-1RA in clinical testing

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