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Notably, previous studies have reported that intravenous Exenatide (Exendin-4) infusion does not significantly alter fasting glucagon secretion in humans 39 , supporting the expectation that genome editing-mediated Exe4 secretion would similarly exert minimal disruption

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PAS was expressed on the surface of fish-derived Lactococcus lactis ZHY1 (termed here PAS-ZHY) to treat fatty liver and intestinal barrier damage that are widespread in farmed fish [57,58]