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In recent years, extensive literature has reported that a variety of signaling pathways and transcription factors are involved in the fat differentiation process of WAT, such as the NOS pathway, neuropeptide S [87] pathway, SIRT1 [88] pathway, STAT3 [89], bone morphogenetic protein 4 (BMP4) [90] pathway, etc

These results represent some of the most significant weight reductions ever achieved with a single medication in obesity research

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doi:10.1016/j.bbrc.2013.03.010 115
