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Increases in cAMP are cell-specific, where GLP-1 failed to induce any detectable changes in alpha cells at a concentration of 1 nmol/L but was able to cause a dose-dependent increase in cAMP in beta cells, with a significant physiologic effect beginning at 10 pmol/L [72]
The Muscle Loss Problem Nobody Talks About Studies show that 2540% of weight lost on GLP-1 medications can come from lean muscle mass not fat
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