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Description
Despite several drugs having been developed to treat obesity, they have limited efficacy, yet significant side effects such as cardiovascular and cerebrovascular problems, cancer, or psychological problems like depression or suicidal ideation (Mller et al., 2022)

That's because the drug works by targeting three gut hormones, including one called glucagon, which increases energy expenditure
Like GIP, GLP-1 is rapidly degraded by DPPIV, limiting circulating levels

Rybelsus is approved for T2D at 3, 7, or 14 mg daily

Ngo-Hamilton says
