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More specifically speaking, the mechanism potentially involved downregulation of macrophage CD11b, which played a vital role in monocyte adhesion, as well as decreased expression of macrophage modulators including CXCL-10, CXCL-1, C-C motif chemokine ligand-1 (CCL-2) and tissue inhibitor of metal protease-1 (TIMP-1) (Robinson et al., 2015)
& Scholtz, J

[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Sun F, Chai S, Yu K, et al

You cannot simply take Akkermansia alone and expect the same results

Virili C, Fallahi P, Antonelli A, Benvenga S, Centanni M