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Approved Alternatives Available Through NHS and Private Clinics MHRA-approved options include semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro), both recommended by NICE for weight management within specialist services under defined eligibility criteria

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NDI-010976 is an inhibitor of both ACC1 and ACC2, which was well tolerated and resulted in profound dose-dependent inhibition of hepatic de novo lipogenesis in overweight male adults in a randomized, controlled crossover trial