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Phase 3 trials are specifically monitoring cardiovascular outcomes, and anyone with a pre-existing heart condition would need careful assessment before starting retatrutide assuming it gains approval

Because it is still in the clinical trial phase globally, its long-term safety profile and benefit-risk balance are still being evaluated

10.1056/NEJMoa1603827 [EL 1

Adjusting amount and timing often helps
This depends on your priorities and circumstances
