semaglutide for alcohol shows promise in reducing cravings alcohol, heavy drinking Does weight loss, diabetes drug

Side effect patterns when transitioning between GLP-1 medications The most common side effects during the switch are gastrointestinal: nausea, vomiting, diarrhea, constipation, and abdominal discomfort

Gabanyi, I

Although a single RCT failed to observe a statistically significant improvement in HOMA-IR (85), this discrepancy is more likely attributable to limited sample sizes, restricted follow-up windows, and heterogeneity in baseline metabolic phenotypes rather than a lack of efficacy

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In clinical trials such as the STEP programme for semaglutide 2.4mg (Wegovy), fatigue was reported more frequently in patients receiving the active treatment compared to placebo