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From the incretin concept and the discovery of GLP-1 to todays diabetes therapy
It wins decisively, and for many people this single factor determines the entire decision
J Alzheimers Dis (2013) 37(3):63748
27-34 PIONEER 1 PIONEER 1 compared the efficacy and safety of oral semaglutide as monotherapy with placebo in patients with T2DM managed by diet and exercise alone
They found that the cost of tirzepatide was about $197,000 per additional quality adjusted life year (QALY), and the cost of semaglutide was about $468,000 per QALY
