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While the clinical effects of tirzepatide have been very encouraging, important questions remain as to the mechanism of action
Bitter Melon helps support metabolism, while Citrus Bergamot and Fenugreek contribute to lipid metabolism and digestive comfort

Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance

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