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While its still early days for a large-scale population study of how HRT and Ozempic interact, there is evidence that in tandem, the two are in effect a turbo-powered weight-loss solution: A scientific study published this year found that postmenopausal women using hormone replacement therapy and semaglutide had a higher total body weight loss at three, six, nine and 12-month markers than women using semaglutide alone

*p-value for interaction between treatment and CV risk quartile

Wilson JM et al (2020) The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes

Weve written at length about why weight loss can sometimes increase subluxation frequency in those with hypermobility, because losing the muscle tissue that was providing joint support takes away a layer of protection

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