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After eight weeks of supplementation at a dose of 750 mg/kg body weight, mild abnormalities in intestinal and liver function were observed, leading to increased inflammation and compromised integrity of the intestinal barrier []

(New England Journal of Medicine) Why it sits in a different bucket than GLP-1 peptides GLP-1 peptides are generally appetite/satiety signalling first. Tesamorelin is more hormonal axis + fat distribution (VAT) first. (ScienceDirect) For a direct comparison of the leading compounds studied for fat reduction, including GLP-1, dual and triple receptor agonists, see our breakdown of the best peptides for weight loss

The medication has not been studied in nursing mothers, and the potential effects on breast milk and infant health are unknown