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Patients with type 2 diabetes have higher baseline rates of anxiety, making it difficult to distinguish medication effects from underlying psychological comorbidity

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Laursen JC, Sndergaard-Heinrich N, de Melo JML et al (2021) Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: a randomised, double-blind, placebo-controlled crossover trial

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They compared individuals using GLP-1RAs with those on more traditional antihyperglycemics, such as sulfonylureas, DPP-4 inhibitors, and SGLT2 inhibitors